Manscript Submission

EVALUATION OF IN-VITRO FREE RADICAL SCAVENGING ACTIVITY OF CINNAMOMUM ZEYLANICUM BARK EXTRACT

Wasim Raja
Central Laboratory Facility, Chhattisgarh Council of Science and Technology, Raipur, Chhattisgarh, India
Jainab Ahmed
School of Studies in Chemical and Biological Sciences, MATS University, Raipur, Chhattisgarh, India
Heena Parwin
School of Studies in Chemical and Biological Sciences, MATS University, Raipur, Chhattisgarh, India

Antioxidant activity , Fenton Reaction ,Hydroxyl radical , ascorbic acid ,Cinnamomum zeylanicum ,TBARS ,

There has been growing interest in the health benefits associated with natural compounds and have been demonstrated with the emphasis on antioxidants. Phenolics in fruits, vegetables, herbs and spices possess potent antioxidant, anti-inflammatory, antimutagenic and anticarcinogenic activities. The present study focused on the antioxidant activity of Cinnamomum zeylanicum Linn bark under in vitro conditions. The dried bark of Cinnamomum zeylanicum was extracted with methanol using a Soxhlet extractor. The total phenolics content of bark as determined by Fenton reaction and was found to be good antioxidant activity as different dose concentrations. . The Reducing power of extract was carried out with ascorbic acid as a standard reducing agent. All the analysis was made with the use of UV-Visible Spectrophotometer. In this plant Cinnamomum zeylanicum bark extract there was a remarkable concentration dependent free radical scavenging and reducing power was exhibited. These findings demonstrated that Cinnamomum zeylanicum possess free radical and hydroxyl radical scavenging activity as well as antioxidant activity in vitro. In conclusion the present study indicates that Cinnamomum zeylanicum may be a potential source of natural antioxidant. The results suggested that Cinnamomum zeylanicum Linn bark could serve as a potential source of antioxidant and can be used in any preparations for combating free radical mediated damage to the body

6 , 2 , 2016

58 - 61