Manscript Submission

ANTIHYPERGLYCEMIC POTENTIAL OF ROOTS OF COLEUS FORSKOHLII BRIQ & DAUCUS CAROTA LINN

The present work assists the credit of the plant material for further investigation and form an important aspect of drug studies. The findings of the present study suggest it could be a potential source of natural antioxidant that could have great importance as therapeutic agents in preventing or slowing the progress of aging and age associated oxidative stress related degenerative diseases and other related diseases. All the obtained extracts were dried and weighed. The percentage yield of each plant was calculated as per standard method. The weighed extract of each plant drug was stored in desiccators for further use. The yields were found to be 11.50g of petroleum ether extract with semisolid mass of brown colour, 16.02g of Methanol extract with Orange-Black colour for Achyranthes aspera leaves. The plant extracts showed no toxicity at a maximum dose of 2000 mg/kg. The methanolic extracts of selected herbal drugs could be formulated into effective hypolipidemic dosage form. This may be due to the synergistic effect of the combined extracts. Thus the results of the present investigation clearly indicated that the selected medicinal plants possess good anti hyerlipidemic activity and led to the development of new Herbal formulation possessing anti hyperlipidemic activity. The results found are encouraging for further studies on the selected plants and to identify the bioactive compounds