Manscript Submission

FORMULATION OF HERBAL CREAM WITH CURCUMIN LOADED LIPOSOMES

Curcumin is the active ingredient in the traditional herbal remedy and dietary spice turmeric (Curcuma longa). Curcumin has a surprisingly wide range of beneficial properties, including anti-inflammatory, antioxidant, chemo preventive and chemotherapeutic activity. Curcumin is remarkably non-toxic and exhibits limited bioavailability. Curcumin exhibits great promise as a therapeutic agent, and is currently in human clinical trials for a variety of conditions, including multiple myeloma, pancreatic cancer, myelodysplastic syndromes, colon cancer, psoriasis and Alzheimer’s disease. The pro-liposomes generally administrated by orally, topically and parentally and mainly used in cosmetic and hair technologies, diagnostic purpose, sustained release formulations and as good carriers in gene delivery. Various methods to formulate pro-liposomes (Film-deposition carrier method, Spray drying method, Fluidized-bed method